close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1256Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. (128 aa)    
Predicted Functional Partners:
AF_0208
Signal-transducing histidine kinase; Similar to PID:1001492 PID:1001594 percent identity: 27.88; identified by sequence similarity; putative.
 
 
 
 0.775
AF_1515
Signal-transducing histidine kinase; Similar to SP:P45670 PID:599601 percent identity: 24.05; identified by sequence similarity; putative.
 
 
 
 0.771
AF_1044
Purine-binding chemotaxis protein (cheW); Similar to GB:M26411 SP:P21821 PID:148348 percent identity: 40.41; identified by sequence similarity; putative.
  
 
 0.758
AF_2109
Signal-transducing histidine kinase; Similar to GB:M29450 SP:P16497 GB:M31067 PID:143333 PID:143631 percent identity: 26.96; identified by sequence similarity; putative.
 
 
 
 0.758
AF_0021
Signal-transducing histidine kinase; Similar to PID:950652 percent identity: 26.11; identified by sequence similarity; putative.
 
 
 
 0.756
AF_1259
Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative.
     
 0.754
AF_1184
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 29.81; identified by sequence similarity; putative.
 
 
 
 0.751
AF_1639
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 29.91; identified by sequence similarity; putative.
 
 
 
 0.748
AF_1043
Predicted coding region AF_1043; Hypothetical protein; identified by GeneMark; putative.
   
 
 0.746
srp19
Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
       0.739
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (26%) [HD]