Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1256Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. (128 aa)    
Predicted Functional Partners:
AF_1259
Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative.
     
 0.751
trmG10
Conserved hypothetical protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity); Belongs to the methyltransferase superfamily. Trm-G10 family.
       0.732
srp19
Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
       0.732
AF_0208
Signal-transducing histidine kinase; Similar to PID:1001492 PID:1001594 percent identity: 27.88; identified by sequence similarity; putative.
 
 
 
 0.702
AF_1043
Predicted coding region AF_1043; Hypothetical protein; identified by GeneMark; putative.
   
 
 0.698
AF_1515
Signal-transducing histidine kinase; Similar to SP:P45670 PID:599601 percent identity: 24.05; identified by sequence similarity; putative.
 
 
 
 0.697
argF
Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
     
 0.690
AF_2109
Signal-transducing histidine kinase; Similar to GB:M29450 SP:P16497 GB:M31067 PID:143333 PID:143631 percent identity: 26.96; identified by sequence similarity; putative.
 
 
 
 0.680
AF_0021
Signal-transducing histidine kinase; Similar to PID:950652 percent identity: 26.11; identified by sequence similarity; putative.
 
 
 
 0.678
AF_1184
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 29.81; identified by sequence similarity; putative.
 
 
 
 0.671
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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