node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_0216 | rpoL | AF_0216 | AF_0207 | L-isoaspartyl protein carboxyl methyltransferase PimT, putative; Similar to GB:L77117 SP:Q57598 PID:1590899 percent identity: 35.51; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.402 |
AF_0216 | rtcA | AF_0216 | AF_1435 | L-isoaspartyl protein carboxyl methyltransferase PimT, putative; Similar to GB:L77117 SP:Q57598 PID:1590899 percent identity: 35.51; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | 0.838 |
AF_0216 | tmcA | AF_0216 | AF_1522 | L-isoaspartyl protein carboxyl methyltransferase PimT, putative; Similar to GB:L77117 SP:Q57598 PID:1590899 percent identity: 35.51; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.817 |
AF_0216 | trm1 | AF_0216 | AF_0815 | L-isoaspartyl protein carboxyl methyltransferase PimT, putative; Similar to GB:L77117 SP:Q57598 PID:1590899 percent identity: 35.51; identified by sequence similarity; putative. | N2,N2-dimethylguanosine tRNA methyltransferase (trm1); Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.538 |
AF_0216 | trmG10 | AF_0216 | AF_1257 | L-isoaspartyl protein carboxyl methyltransferase PimT, putative; Similar to GB:L77117 SP:Q57598 PID:1590899 percent identity: 35.51; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity); Belongs to the methyltransferase superfamily. Trm-G10 family. | 0.719 |
AF_1256 | AF_1259 | AF_1256 | AF_1259 | Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. | Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative. | 0.754 |
AF_1256 | purQ | AF_1256 | AF_1260 | Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. | Phosphoribosylformylglycinamidine synthase I (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to a [...] | 0.640 |
AF_1256 | srp19 | AF_1256 | AF_1258 | Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. | Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.739 |
AF_1256 | trmG10 | AF_1256 | AF_1257 | Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity); Belongs to the methyltransferase superfamily. Trm-G10 family. | 0.732 |
AF_1259 | AF_1256 | AF_1259 | AF_1256 | Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative. | Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. | 0.754 |
AF_1259 | purQ | AF_1259 | AF_1260 | Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative. | Phosphoribosylformylglycinamidine synthase I (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to a [...] | 0.659 |
AF_1259 | srp19 | AF_1259 | AF_1258 | Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative. | Signal recognition particle, subunit SRP19 (srp19); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.786 |
AF_1259 | trmG10 | AF_1259 | AF_1257 | Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity); Belongs to the methyltransferase superfamily. Trm-G10 family. | 0.786 |
nob1 | rpoL | AF_0385 | AF_0207 | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family. | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.564 |
nob1 | rtcA | AF_0385 | AF_1435 | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family. | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | 0.744 |
nob1 | tmcA | AF_0385 | AF_1522 | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family. | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.751 |
nob1 | trm1 | AF_0385 | AF_0815 | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family. | N2,N2-dimethylguanosine tRNA methyltransferase (trm1); Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.573 |
nob1 | trmG10 | AF_0385 | AF_1257 | Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end (By similarity); Belongs to the PINc/VapC protein family. | Conserved hypothetical protein; Catalyzes the adenosylmethionine-dependent methylation of the exocyclic amino group (N(2)) of guanosine at position 10 of various tRNAs. Acts via a two-step process that leads to the formation of either N(2)-monomethyl (m(2)G) or N(2)-dimethylguanosine (m(2)(2)G) (By similarity); Belongs to the methyltransferase superfamily. Trm-G10 family. | 0.676 |
purQ | AF_1256 | AF_1260 | AF_1256 | Phosphoribosylformylglycinamidine synthase I (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to a [...] | Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative. | 0.640 |
purQ | AF_1259 | AF_1260 | AF_1259 | Phosphoribosylformylglycinamidine synthase I (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to a [...] | Inosine monophosphate dehydrogenase, putative; Similar to GB:L77117 SP:Q57647 PID:1498962 percent identity: 51.61; identified by sequence similarity; putative. | 0.659 |