Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1279Conserved hypothetical protein; Similar to GB:L77117 SP:Q58707 PID:1591950 percent identity: 30.05; identified by sequence similarity; putative. (249 aa)    
Predicted Functional Partners:
AF_1278
Conserved hypothetical protein; Similar to GB:L77117 PID:1500366 percent identity: 57.80; identified by sequence similarity; putative.
 
     0.810
argB
Acetylglutamate kinase (argB); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
       0.798
AF_1358
Phosphate ABC transporter, permease protein (pstA); Similar to GB:L10328 SP:P07654 GB:K01992 GB:X02723 PID:147258 percent identity: 34.07; identified by sequence similarity; putative.
     
 0.632
AF_1395
Conserved hypothetical protein; Similar to GB:L77117 PID:1592047 percent identity: 45.41; identified by sequence similarity; putative; In the N-terminal section; belongs to the UPF0200 family.
       0.624
AF_1505
Predicted coding region AF_1505; Hypothetical protein; identified by GeneMark; putative.
       0.624
AF_1357
Phosphate ABC transporter, permease protein (pstC); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
     
 0.623
pstB
Phosphate ABC transporter, ATP-binding protein (pstB); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.620
AF_1360
Phosphate ABC transporter, regulatory protein (phoU); Plays a role in the regulation of phosphate uptake.
       0.602
AF_0401
Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative.
 
  
 0.561
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
       0.504
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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