Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1285Cell division control protein, AAA family, putative; Similar to GB:L77117 SP:Q58889 PID:1592130 percent identity: 49.28; identified by sequence similarity; putative; Belongs to the AAA ATPase family. (352 aa)    
Predicted Functional Partners:
AF_1286
Acetoin utilization protein, putative; Similar to PID:1177686 percent identity: 35.06; identified by sequence similarity; putative.
       0.639
rpl21e
LSU ribosomal protein L21E (rpl21E); Similar to GB:L77117 SP:P54013 PID:1590841 percent identity: 53.19; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
    
   0.636
AF_0849
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57857 PID:1499205 percent identity: 43.16; identified by sequence similarity; putative.
  
     0.522
rpl2
LSU ribosomal protein L2P (rpl2P); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
   0.516
AF_1936
Conserved hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
  
     0.506
AF_0731
Cobalt transport ATP-binding protein (cbiO-1); Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
  
     0.498
ileS
isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
  
 
   0.481
AF_0984
ABC transporter, ATP-binding protein; Similar to SP:P46903 PID:973330 PID:2415726 GB:AL009126 percent identity: 35.16; identified by sequence similarity; putative.
  
     0.468
AF_1554
Thioredoxin reductase (trxB); Similar to PID:1171125 SP:P52213 percent identity: 45.21; identified by sequence similarity; putative.
 
     0.460
AF_1160
H+-transporting ATP synthase, subunit K (atpK-1); Similar to GB:L77117 SP:Q57674 PID:1590959 percent identity: 46.27; identified by sequence similarity; putative.
  
  
  0.438
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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