Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1287acetyl-CoA synthetase (acs-6); Similar to GB:L17309 SP:P39062 PID:348053 PID:2293224 GB:AL009126 percent identity: 34.29; identified by sequence similarity; putative. (586 aa)    
Predicted Functional Partners:
AF_0333
4-hydroxyphenylacetate-3-hydroxylase (hpaA-1); Similar to PID:974146 percent identity: 22.35; identified by sequence similarity; putative.
    
  0.900
AF_1027
4-hydroxyphenylacetate-3-hydroxylase (hpaA-3); Similar to PID:974146 percent identity: 21.03; identified by sequence similarity; putative.
    
  0.900
AF_0967
3-ketoacyl-CoA thiolase (acaB-9); Similar to GB:L77117 PID:1592180 percent identity: 33.67; identified by sequence similarity; putative.
  
  
 0.564
AF_2243
3-ketoacyl-CoA thiolase (fadA-3); Similar to GB:M87049 SP:P21151 GB:M59368 GB:M74164 PID:145901 percent identity: 40.83; identified by sequence similarity; putative.
  
  
 0.564
AF_0969
Proline permease (putP-2); Similar to SP:P07117 GB:L01132 GB:L01133 GB:L01150 GB:L01151 percent identity: 27.40; identified by sequence similarity; putative; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.536
AF_0922
Predicted coding region AF_0922; Hypothetical protein; identified by GeneMark; putative.
  
 
 0.524
AF_0963
enoyl-CoA hydratase (fad-3); Similar to PID:755067 percent identity: 48.56; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.518
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.516
AF_1286
Acetoin utilization protein, putative; Similar to PID:1177686 percent identity: 35.06; identified by sequence similarity; putative.
  
  
 0.511
AF_2219
methylmalonyl-CoA mutase, subunit alpha, C-terminus (mcmA2); Similar to GB:L30136 PID:463175 percent identity: 48.72; identified by sequence similarity; putative.
     
 0.508
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (28%) [HD]