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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1290Conserved hypothetical protein; Similar to SP:P45515 PID:493088 percent identity: 31.54; identified by sequence similarity; putative. (162 aa)    
Predicted Functional Partners:
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
 
   
 0.934
AF_1289
Conserved hypothetical protein; May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone (By similarity).
       0.831
AF_1292
Conserved hypothetical protein; Similar to GB:L77117 PID:1592182 percent identity: 36.90; identified by sequence similarity; putative.
 
     0.748
AF_1291
3-ketoacyl-CoA thiolase (acaB-11); Similar to GB:L77117 PID:1592180 percent identity: 40.10; identified by sequence similarity; putative.
       0.716
AF_1293
acyl-CoA dehydrogenase (acd-9); Similar to SP:P45867 PID:853760 GB:AL009126 percent identity: 45.77; identified by sequence similarity; putative.
       0.713
AF_0722
Cobalamin biosynthesis precorrin-6Y methylase (cbiE); Similar to GB:L77117 PID:1592152 percent identity: 32.40; identified by sequence similarity; putative.
 
   
 0.585
AF_0276
Conserved hypothetical protein; Similar to GB:L77117 PID:1500495 percent identity: 40.12; identified by sequence similarity; putative; Belongs to the UPF0284 family.
     
 0.579
AF_1400
Conserved hypothetical protein; Similar to GB:L77117 PID:1500511 percent identity: 32.53; identified by sequence similarity; putative.
  
    0.562
AF_0725
Cobalamin biosynthesis precorrin methylase (cbiG); Similar to PID:1651952 percent identity: 30.69; identified by sequence similarity; putative.
 
   
 0.510
cbiT
Cobalamin biosynthesis precorrin-8W decarboxylase (cbiT); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
     
 0.504
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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