Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1297Cell division control protein 48, AAA family (cdc48-1); Similar to GB:L77117 SP:Q58556 PID:1591785 percent identity: 69.10; identified by sequence similarity; putative; Belongs to the AAA ATPase family. CDC48 subfamily. (733 aa)    
Predicted Functional Partners:
AF_1296
Small heat shock protein (hsp20-1); Similar to GB:L77117 SP:Q57733 PID:1591008 percent identity: 52.27; identified by sequence similarity; putative; Belongs to the small heat shock protein (HSP20) family.
 
 
 0.979
AF_1298
Predicted coding region AF_1298; Hypothetical protein; identified by GeneMark; putative.
     
 0.975
AF_2098
Cell division control protein 48, AAA family (cdc48-2); Similar to GB:X79560 SP:P46464 PID:517390 percent identity: 61.98; identified by sequence similarity; putative.
  
  
 
0.902
AF_1971
Small heat shock protein (hsp20-2); Similar to SP:P19244 percent identity: 38.14; identified by sequence similarity; putative; Belongs to the small heat shock protein (HSP20) family.
  
 
 0.885
thsB
Thermosome, subunit beta (thsB); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 0.883
thsA
Thermosome, subunit alpha (thsA); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 0.876
rpl40e
LSU ribosomal protein L40E (rpl40E); Similar to GB:L77117 SP:P54058 PID:1591423 percent identity: 73.33; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 0.837
AF_0866
Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
  
  0.802
AF_0130
Acetylpolyamine aminohydrolase (aphA); Probable deacetylase; Belongs to the histone deacetylase family.
   
 0.793
AF_0690
Predicted coding region AF_0690; Hypothetical protein; identified by GeneMark; putative.
   
 0.793
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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