Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_1309Conserved hypothetical protein; Similar to PID:1653859 percent identity: 32.14; identified by sequence similarity; putative. (211 aa)    
Predicted Functional Partners:
AF_1308
Thymidylate kinase, putative; Similar to GB:L77117 SP:Q57741 PID:1591015 percent identity: 26.32; identified by sequence similarity; putative.
 
     0.968
ribL
Glycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
   
 
 0.717
AF_0706
Conserved hypothetical protein; Similar to GB:L77117 PID:1591604 percent identity: 36.12; identified by sequence similarity; putative.
 
     0.623
AF_1310
ISA0963-3, putative transposase; Similar to GP:1143021 percent identity: 33.52; identified by sequence similarity; putative.
       0.550
AF_0707
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58767 PID:1592017 percent identity: 43.83; identified by sequence similarity; putative.
   
 
 0.461
uppS
Conserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
   
 
 0.461
AF_0404
4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
   
 0.434
AF_1311
Oxygen-independent coproporphyrinogen III oxidase, putative; Similar to SP:P54304 PID:1303805 GB:AL009126 percent identity: 27.13; identified by sequence similarity; putative.
       0.422
AF_0616
Conserved hypothetical protein; Similar to PID:1652163 percent identity: 28.15; identified by sequence similarity; putative.
  
     0.407
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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