| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_1317 | AF_1318 | AF_1317 | AF_1318 | Predicted coding region AF_1317; Hypothetical protein; identified by GeneMark; putative. | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | 0.773 |
| AF_1318 | AF_1317 | AF_1318 | AF_1317 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Predicted coding region AF_1317; Hypothetical protein; identified by GeneMark; putative. | 0.773 |
| AF_1318 | albA2 | AF_1318 | AF_1956 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Conserved hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.460 |
| AF_1318 | cas1-2 | AF_1318 | AF_2435 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.825 |
| AF_1318 | fen | AF_1318 | AF_0264 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.408 |
| AF_1318 | hisG | AF_1318 | AF_0590 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | ATP phosphoribosyltransferase (hisG); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.591 |
| AF_1318 | pyrF | AF_1318 | AF_0929 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Conserved hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.471 |
| AF_1318 | sfsA | AF_1318 | AF_1516 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 30.96; identified by sequence similarity; putative; Belongs to the SfsA family. | 0.822 |
| AF_1318 | thsA | AF_1318 | AF_2238 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Thermosome, subunit alpha (thsA); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family. | 0.820 |
| AF_1318 | trpA | AF_1318 | AF_1599 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Tryptophan synthase, subunit alpha (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.410 |
| AF_1318 | trpB1 | AF_1318 | AF_1600 | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | Tryptophan synthase, subunit beta (trpB-2); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.471 |
| albA2 | AF_1318 | AF_1956 | AF_1318 | Conserved hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | 0.460 |
| albA2 | fen | AF_1956 | AF_0264 | Conserved hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.428 |
| albA2 | hisG | AF_1956 | AF_0590 | Conserved hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | ATP phosphoribosyltransferase (hisG); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.472 |
| cas1-2 | AF_1318 | AF_2435 | AF_1318 | Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | 0.825 |
| cas1-2 | fen | AF_2435 | AF_0264 | Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.475 |
| fen | AF_1318 | AF_0264 | AF_1318 | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA. | 0.408 |
| fen | albA2 | AF_0264 | AF_1956 | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | Conserved hypothetical protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.428 |
| fen | cas1-2 | AF_0264 | AF_2435 | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. | 0.475 |
| fen | pyrF | AF_0264 | AF_0929 | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | Conserved hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.601 |
