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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1330Pyruvate formate-lyase activating enzyme (act-3); Similar to GB:L77117 SP:Q58218 PID:1499631 percent identity: 45.81; identified by sequence similarity; putative. (336 aa)    
Predicted Functional Partners:
AF_1969
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58220 PID:1592310 percent identity: 55.84; identified by sequence similarity; putative.
     0.963
AF_2310
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57846 PID:1591108 percent identity: 47.01; identified by sequence similarity; putative; Belongs to the MEMO1 family.
     0.939
AF_1449
Pyruvate formate-lyase 2 (pflD); Similar to SP:P32674 GB:U00006 PID:396298 GB:U00096 PID:1790388 percent identity: 37.81; identified by sequence similarity; putative.
  
  
 0.837
AF_1331
Predicted coding region AF_1331; Hypothetical protein; identified by GeneMark; putative.
       0.781
AF_1396
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58217 PID:1591499 percent identity: 44.68; identified by sequence similarity; putative.
  
    0.611
rpl44e
LSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA.
       0.558
AF_1332
Predicted coding region AF_1332; Hypothetical protein; identified by GeneMark; putative.
       0.554
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
  
  
 0.545
rps27e
SSU ribosomal protein S27E (rps27E); Similar to GB:L77117 SP:P54028 PID:1499029 percent identity: 49.02; identified by sequence similarity; putative.
       0.537
AF_1938
Conserved hypothetical protein; Catalyzes the reversible conversion of a variety of acids to the corresponding acyl-CoA esters. Shows the highest activity with the aryl acids, indoleacetate and phenylacetate, as compared to acetate. In the reverse direction, phenylacetyl-CoA is the best substrate. Seems to be involved primarily in the degradation of aryl-CoA esters to the corresponding acids. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters. In the C-terminal section; belongs to the acetate CoA ligase alpha subunit family.
     
 0.525
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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