Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_1330Pyruvate formate-lyase activating enzyme (act-3); Similar to GB:L77117 SP:Q58218 PID:1499631 percent identity: 45.81; identified by sequence similarity; putative. (336 aa)    
Predicted Functional Partners:
AF_1969
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58220 PID:1592310 percent identity: 55.84; identified by sequence similarity; putative.
     0.971
AF_2310
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57846 PID:1591108 percent identity: 47.01; identified by sequence similarity; putative; Belongs to the MEMO1 family.
     0.943
AF_1396
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58217 PID:1591499 percent identity: 44.68; identified by sequence similarity; putative.
  
    0.782
AF_1331
Predicted coding region AF_1331; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_1449
Pyruvate formate-lyase 2 (pflD); Similar to SP:P32674 GB:U00006 PID:396298 GB:U00096 PID:1790388 percent identity: 37.81; identified by sequence similarity; putative.
  
  
 0.759
thiL
Thiamine monophosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.624
rpl44e
LSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA.
       0.557
AF_1332
Predicted coding region AF_1332; Hypothetical protein; identified by GeneMark; putative.
       0.554
rps27e
SSU ribosomal protein S27E (rps27E); Similar to GB:L77117 SP:P54028 PID:1499029 percent identity: 49.02; identified by sequence similarity; putative.
       0.537
AF_1961
Pyruvate formate-lyase activating enzyme (pflX); Similar to PID:1016358 percent identity: 50.15; identified by sequence similarity; putative.
     
 0.532
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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