Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_1337Conserved hypothetical protein; Similar to GB:L77117 PID:1591827 percent identity: 44.02; identified by sequence similarity; putative. (692 aa)    
Predicted Functional Partners:
cobD
Cobalamin biosynthesis protein (cbiB); Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
    0.798
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
 
     0.692
AF_0746
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57608 PID:1590906 percent identity: 32.75; identified by sequence similarity; putative.
  
    0.655
ribL
Glycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
       0.624
AF_1335
Predicted coding region AF_1335; Hypothetical protein; identified by GeneMark; putative.
       0.572
AF_1834
Conserved hypothetical protein; Similar to GB:L77117 PID:1500336 percent identity: 26.32; identified by sequence similarity; putative.
  
     0.570
AF_2363
Conserved hypothetical protein; Similar to GB:L77117 PID:1500295 percent identity: 54.77; identified by sequence similarity; putative.
  
     0.569
cofC
Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.566
AF_1966
Conserved hypothetical protein; Similar to GB:L77117 PID:1591643 percent identity: 28.65; identified by sequence similarity; putative.
  
     0.565
AF_1298
Predicted coding region AF_1298; Hypothetical protein; identified by GeneMark; putative.
  
     0.554
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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