Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1365Hydrogenase expression/formation protein (hypE); Similar to GB:L77117 SP:Q58089 PID:1591391 percent identity: 51.52; identified by sequence similarity; putative. (344 aa)    
Predicted Functional Partners:
AF_1370
Hydrogenase expression/formation protein (hypD); Similar to GB:L77117 SP:Q58400 PID:1591656 percent identity: 46.02; identified by sequence similarity; putative.
 
 0.998
AF_1366
Hydrogenase expression/formation regulatory protein (hypF); Similar to GB:L77117 PID:1591430 percent identity: 45.08; identified by sequence similarity; putative.
 
 
 0.997
AF_1369
Hydrogenase expression/formation protein (hypC); Similar to GB:L77117 SP:Q57653 PID:1498975 percent identity: 40.54; identified by sequence similarity; putative.
 
 
 0.990
hypA
Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.947
AF_1368
Hydrogenase expression/formation protein (hypB); Similar to GB:L77117 SP:Q57884 PID:1591146 percent identity: 54.37; identified by sequence similarity; putative.
 
  
 0.908
AF_1381
F420-nonreducing hydrogenase (vhtG); Similar to PID:602582 percent identity: 46.11; identified by sequence similarity; putative.
 
   
 0.876
AF_1380
F420-nonreducing hydrogenase (vhtA); Similar to PID:602583 percent identity: 34.82; identified by sequence similarity; putative.
 
   
 0.821
AF_1372
Methylviologen-reducing hydrogenase, subunit alpha (vhuA); Similar to GB:L77117 PID:1591820 percent identity: 39.40; identified by sequence similarity; putative.
 
   
 0.694
AF_1378
F420-nonreducing hydrogenase (vhtD-2); Similar to PID:1016350 percent identity: 33.11; identified by sequence similarity; putative.
 
   
 0.691
AF_0299
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58021 PID:1591313 percent identity: 41.11; identified by sequence similarity; putative.
       0.624
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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