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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1368Hydrogenase expression/formation protein (hypB); Similar to GB:L77117 SP:Q57884 PID:1591146 percent identity: 54.37; identified by sequence similarity; putative. (221 aa)    
Predicted Functional Partners:
hypA
Hydrogenase expression/formation protein (hypA); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.994
AF_1370
Hydrogenase expression/formation protein (hypD); Similar to GB:L77117 SP:Q58400 PID:1591656 percent identity: 46.02; identified by sequence similarity; putative.
 
  
 0.975
AF_1369
Hydrogenase expression/formation protein (hypC); Similar to GB:L77117 SP:Q57653 PID:1498975 percent identity: 40.54; identified by sequence similarity; putative.
  
  
 0.942
AF_1365
Hydrogenase expression/formation protein (hypE); Similar to GB:L77117 SP:Q58089 PID:1591391 percent identity: 51.52; identified by sequence similarity; putative.
 
  
 0.912
AF_1366
Hydrogenase expression/formation regulatory protein (hypF); Similar to GB:L77117 PID:1591430 percent identity: 45.08; identified by sequence similarity; putative.
 
   
 0.880
AF_1989
Peptidyl-prolyl cis-trans isomerase (slyD); Similar to GB:L77117 SP:Q58235 PID:1591512 percent identity: 34.38; identified by sequence similarity; putative.
    
 
 0.858
AF_1381
F420-nonreducing hydrogenase (vhtG); Similar to PID:602582 percent identity: 46.11; identified by sequence similarity; putative.
 
  
 0.832
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.590
AF_1380
F420-nonreducing hydrogenase (vhtA); Similar to PID:602583 percent identity: 34.82; identified by sequence similarity; putative.
 
  
 0.584
AF_0743
Conserved hypothetical protein; Transcriptional regulator.
 
   
 0.579
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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