Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_1373Methylviologen-reducing hydrogenase, subunit gamma (vhuG); Similar to GB:X61204 PID:44798 PID:1747407 percent identity: 38.60; identified by sequence similarity; putative. (293 aa)    
Predicted Functional Partners:
AF_1372
Methylviologen-reducing hydrogenase, subunit alpha (vhuA); Similar to GB:L77117 PID:1591820 percent identity: 39.40; identified by sequence similarity; putative.
 
 0.999
AF_1374
Methylviologen-reducing hydrogenase, subunit delta (vhuD); Similar to GB:J04540 PID:149731 GB:AE000666 percent identity: 41.67; identified by sequence similarity; putative.
 0.999
AF_0662
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.998
AF_1375
Heterodisulfide reductase, subunit B (hdrB); Similar to GB:L77117 PID:1591548 percent identity: 36.00; identified by sequence similarity; putative.
 
 0.998
AF_1376
Heterodisulfide reductase, subunit C (hdrC); Similar to GB:L77117 PID:1591457 percent identity: 33.33; identified by sequence similarity; putative.
 
 0.998
AF_1377
Heterodisulfide reductase, subunit A (hdrA-2); Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.998
AF_0271
Heterodisulfide reductase, subunit B, putative; Similar to GB:L77117 PID:1591456 percent identity: 35.33; identified by sequence similarity; putative.
 
 0.991
AF_1238
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.989
AF_1380
F420-nonreducing hydrogenase (vhtA); Similar to PID:602583 percent identity: 34.82; identified by sequence similarity; putative.
 
 
 0.926
AF_0506
Iron-sulfur binding reductase; Similar to GP:1890198 percent identity: 38.50; identified by sequence similarity; putative.
    
 0.915
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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