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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1402Iron (III) ABC transporter, permease protein (hemU-2); Similar to GB:L42023 PID:1007599 PID:1221614 PID:1205706 SP:Q57130 percent identity: 35.22; identified by sequence similarity; putative. (328 aa)    
Predicted Functional Partners:
AF_1401
Iron (III) ABC transporter, ATP-binding protein (hemV-3); Similar to GB:L77117 PID:1591556 percent identity: 35.19; identified by sequence similarity; putative.
 
 0.997
AF_0430
Iron (III) ABC transporter, ATP-binding protein (hemV-1); Similar to GB:L77117 SP:Q57554 PID:1498853 percent identity: 50.40; identified by sequence similarity; putative.
 
 0.992
AF_0432
Iron (III) ABC transporter, ATP-binding protein (hemV-2); Similar to GB:L77117 SP:Q57550 PID:1590868 percent identity: 58.71; identified by sequence similarity; putative.
 
 
 0.978
AF_1400
Conserved hypothetical protein; Similar to GB:L77117 PID:1500511 percent identity: 32.53; identified by sequence similarity; putative.
  
    0.807
AF_1404
Transcriptional regulatory protein, AsnC family; Similar to GB:L10328 SP:P03809 GB:K00826 PID:290592 PID:455179 percent identity: 45.10; identified by sequence similarity; putative.
     
 0.734
AF_1403
Conserved hypothetical protein; Similar to GB:L77117 PID:1592100 percent identity: 58.99; identified by sequence similarity; putative.
       0.723
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
     
 0.692
AF_1405
Conserved hypothetical protein; Similar to GB:L77117 PID:1592081 percent identity: 46.05; identified by sequence similarity; putative.
       0.638
AF_0433
Conserved hypothetical protein; Similar to GB:D15061 SP:P28634 PID:303558 GB:U00096 PID:1552771 percent identity: 39.61; identified by sequence similarity; putative.
  
    0.605
AF_1398
Predicted coding region AF_1398; Hypothetical protein; identified by GeneMark; putative.
  
    0.571
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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