Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_1403Conserved hypothetical protein; Similar to GB:L77117 PID:1592100 percent identity: 58.99; identified by sequence similarity; putative. (219 aa)    
Predicted Functional Partners:
htpX
Heat shock protein (htpX); Similar to GB:L77117 PID:1592249 percent identity: 32.95; identified by sequence similarity; putative; Belongs to the peptidase M48B family.
  
    0.879
AF_1404
Transcriptional regulatory protein, AsnC family; Similar to GB:L10328 SP:P03809 GB:K00826 PID:290592 PID:455179 percent identity: 45.10; identified by sequence similarity; putative.
       0.807
cas21
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Involved in the integration of spacer DNA into the CRISPR cassette (By similarity). Functions as a ssRNA-specific endoribonuclease.
      
 0.800
AF_0116
Uroporphyrinogen III synthase (hemD); Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
    0.798
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Incorrectly charged aminoacyl-tRNA(Ala) is also edited in situ by the editing domain.
  
    0.774
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
  
    0.755
rps4
SSU ribosomal protein S4P (rps4P); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
     
 0.754
cas22
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
      
 0.753
AF_1400
Conserved hypothetical protein; Similar to GB:L77117 PID:1500511 percent identity: 32.53; identified by sequence similarity; putative.
       0.723
AF_1401
Iron (III) ABC transporter, ATP-binding protein (hemV-3); Similar to GB:L77117 PID:1591556 percent identity: 35.19; identified by sequence similarity; putative.
       0.723
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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