Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1410ISA0963-5, putative transposase; Similar to GP:1143021 percent identity: 33.52; identified by sequence similarity; putative. (357 aa)    
Predicted Functional Partners:
AF_0382
Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative.
    
 0.657
AF_0780
Predicted coding region AF_0780; Hypothetical protein; identified by GeneMark; putative.
    
 0.657
AF_1409
Modification methylase, type III R/M system; Similar to SP:P14827 GB:X17111 PID:41315 percent identity: 31.36; identified by sequence similarity; putative.
 
     0.650
AF_1407
Predicted coding region AF_1407; Hypothetical protein; identified by GeneMark; putative.
       0.520
AF_1408
Predicted coding region AF_1408; Hypothetical protein; identified by GeneMark; putative.
       0.520
rpl40e
LSU ribosomal protein L40E (rpl40E); Similar to GB:L77117 SP:P54058 PID:1591423 percent identity: 73.33; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
  0.503
pcn
Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
  
 0.485
AF_0817
Conserved hypothetical protein; Similar to GB:L77117 PID:1500447 percent identity: 42.53; identified by sequence similarity; putative.
    
  0.475
AF_2418
DNA repair protein, putative; Similar to GB:U64315 SP:Q92889 PID:1524411 PID:1905924 percent identity: 28.86; identified by sequence similarity; putative.
    
  0.475
tfs
Transcription-associated protein TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to ind [...]
    
 0.474
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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