Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1415Chloride channel, putative; Similar to PID:1653666 percent identity: 27.29; identified by sequence similarity; putative. (589 aa)    
Predicted Functional Partners:
AF_1414
Dihydropteroate synthase; Similar to GB:L77117 SP:Q57571 PID:1590884 percent identity: 40.82; identified by sequence similarity; putative.
       0.789
thiL
Thiamine monophosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.624
AF_1412
Predicted coding region AF_1412; Hypothetical protein; identified by GeneMark; putative.
 
     0.577
AF_0846
Na+/H+ antiporter (nhe2); Similar to PID:1653577 percent identity: 33.13; identified by sequence similarity; putative.
 
  
 0.530
AF_1413
Surface layer protein B (slgB-2); Similar to PID:602882 percent identity: 29.91; identified by sequence similarity; putative.
       0.522
AF_1330
Pyruvate formate-lyase activating enzyme (act-3); Similar to GB:L77117 SP:Q58218 PID:1499631 percent identity: 45.81; identified by sequence similarity; putative.
       0.503
AF_1417
Aspartate aminotransferase (aspC); Similar to GB:L77117 PID:1591623 percent identity: 49.29; identified by sequence similarity; putative.
     
 0.462
ribL
Glycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
       0.448
AF_0839
TRK potassium uptake system protein (trkH); Similar to GB:U00096 PID:2367317 percent identity: 38.69; identified by sequence similarity; putative.
 
  
 0.443
ribC
Riboflavin synthase (ribC); Similar to GB:L77117 PID:1591811 percent identity: 53.33; identified by sequence similarity; putative; Belongs to the DMRL synthase family.
       0.443
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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