Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_1417Aspartate aminotransferase (aspC); Similar to GB:L77117 PID:1591623 percent identity: 49.29; identified by sequence similarity; putative. (372 aa)    
Predicted Functional Partners:
ribL
Glycerol-3-phosphate cytidyltransferase (taqD); Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
  
  
 0.912
ribC
Riboflavin synthase (ribC); Similar to GB:L77117 PID:1591811 percent identity: 53.33; identified by sequence similarity; putative; Belongs to the DMRL synthase family.
       0.906
AF_0807
L-lactate dehydrogenase, cytochrome-type (lldD); Similar to SP:P33232 GB:L13970 PID:404695 PID:466743 GB:U00096 percent identity: 39.41; identified by sequence similarity; putative.
 
 0.889
AF_0274
Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.
 
 
 0.871
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Incorrectly charged aminoacyl-tRNA(Ala) is also edited in situ by the editing domain.
  
  
 0.840
purD
Phosphoribosylamine--glycine ligase (purD); Similar to GB:L42023 SP:P43845 PID:1005977 PID:1220991 PID:1205135 percent identity: 40.90; identified by sequence similarity; putative.
  
  
 0.829
serA
Phosphoglycerate dehydrogenase (serA); Similar to GB:L77117 PID:1591676 percent identity: 48.77; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.806
fni
Carotenoid biosynthetic gene ERWCRTS, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 0.794
AF_1142
Glucose-1-phosphate cytidylyltransferase (rfbF); Similar to SP:P26396 GB:X56793 GB:X52093 PID:47894 percent identity: 38.61; identified by sequence similarity; putative.
 
    0.754
ribH
Riboflavin synthase, subunit beta (ribE); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
     
 0.730
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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