Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1423Conserved hypothetical protein; Similar to GP:1561567 percent identity: 36.39; identified by sequence similarity; putative. (387 aa)    
Predicted Functional Partners:
AF_1775
Atrazine chlorohydrolase, putative; Similar to GB:L77117 SP:Q58110 PID:1591414 percent identity: 34.39; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
   
 0.700
AF_1834
Conserved hypothetical protein; Similar to GB:L77117 PID:1500336 percent identity: 26.32; identified by sequence similarity; putative.
 
     0.669
AF_1422
Aspartate racemase; Similar to GP:1545809 percent identity: 28.02; identified by sequence similarity; putative.
       0.661
AF_0746
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57608 PID:1590906 percent identity: 32.75; identified by sequence similarity; putative.
 
     0.648
AF_1156
Predicted coding region AF_1156; Hypothetical protein; identified by GeneMark; putative.
  
   0.644
ubiX
Phenylacrylic acid decarboxylase (pad1); Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
  
    0.642
cofD
Conserved hypothetical protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
       0.624
pyrH
Uridylate kinase (pyrH); Catalyzes the reversible phosphorylation of UMP to UDP.
 
     0.617
AF_1835
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57680 PID:1499004 percent identity: 33.08; identified by sequence similarity; putative.
       0.614
fusA
Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
       0.569
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.