Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1432Conserved hypothetical protein; Similar to SP:P38331 PID:536651 percent identity: 30.26; identified by sequence similarity; putative. (173 aa)    
Predicted Functional Partners:
AF_1431
Predicted coding region AF_1431; Hypothetical protein; identified by GeneMark; putative.
       0.787
kptA1
Conserved hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity).
       0.618
AF_0407
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57677 PID:1499001 percent identity: 48.72; identified by sequence similarity; putative.
       0.618
wtpA
Conserved hypothetical protein; Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.
       0.593
AF_1433
Conserved hypothetical protein; Similar to GB:L77117 PID:1591781 percent identity: 31.58; identified by sequence similarity; putative; Belongs to the UPF0215 family.
       0.569
AF_1181
GTP-binding protein; Similar to GP:1732241 percent identity: 36.26; identified by sequence similarity; putative.
       0.516
rtcA
Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
  
    0.509
AF_0205
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57732 PID:1499066 percent identity: 45.73; identified by sequence similarity; putative.
   
    0.500
AF_1550
Conserved hypothetical protein; Similar to GB:L77117 PID:1591933 percent identity: 49.53; identified by sequence similarity; putative.
 
     0.485
AF_0374
P-nitrophenyl phosphatase (pho2); Similar to SP:P19881 PID:1431400 percent identity: 31.52; identified by sequence similarity; putative.
  
  
 0.482
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.