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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1432Conserved hypothetical protein; Similar to SP:P38331 PID:536651 percent identity: 30.26; identified by sequence similarity; putative. (173 aa)    
Predicted Functional Partners:
AF_1431
Predicted coding region AF_1431; Hypothetical protein; identified by GeneMark; putative.
       0.786
AF_0205
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57732 PID:1499066 percent identity: 45.73; identified by sequence similarity; putative.
   
    0.626
AF_1433
Conserved hypothetical protein; Similar to GB:L77117 PID:1591781 percent identity: 31.58; identified by sequence similarity; putative; Belongs to the UPF0215 family.
       0.569
AF_0374
P-nitrophenyl phosphatase (pho2); Similar to SP:P19881 PID:1431400 percent identity: 31.52; identified by sequence similarity; putative.
  
  
 0.563
kptA1
Conserved hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity).
       0.534
AF_0407
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57677 PID:1499001 percent identity: 48.72; identified by sequence similarity; putative.
       0.534
rtcA
Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
  
    0.492
AF_1550
Conserved hypothetical protein; Similar to GB:L77117 PID:1591933 percent identity: 49.53; identified by sequence similarity; putative.
 
     0.484
AF_1434
Predicted coding region AF_1434; Hypothetical protein; identified by GeneMark; putative.
       0.470
pcn
Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
     0.451
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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