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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1444Predicted coding region AF_1444; Hypothetical protein; identified by GeneMark; putative. (410 aa)    
Predicted Functional Partners:
AF_1445
Conserved hypothetical protein; Similar to GP:1524204 percent identity: 26.18; identified by sequence similarity; putative.
 
 
 0.996
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
     
 0.756
AF_2424
Conserved hypothetical protein; Similar to PID:1652337 percent identity: 27.67; identified by sequence similarity; putative.
  
  
 0.606
AF_0404
4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
  
 0.566
AF_2425
Methanol dehydrogenase regulatory protein (moxR); Similar to PID:1001216 PID:1001272 percent identity: 48.33; identified by sequence similarity; putative.
  
  
 0.559
AF_1446
Predicted coding region AF_1446; Hypothetical protein; identified by GeneMark; putative.
       0.557
AF_1447
Predicted coding region AF_1447; Hypothetical protein; identified by GeneMark; putative.
       0.557
cbiA
Cobyrinic acid a,c-diamide synthase (cbiA); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
     
 0.518
hemC
Porphobilinogen deaminase (hemC); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
  
 0.495
AF_1637
Bacteriochlorophyll synthase, 43 kDa subunit (chlP-3); Similar to SP:P26172 PID:46117 percent identity: 27.03; identified by sequence similarity; putative.
 
  
 0.479
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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