Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1452Signal-transducing histidine kinase; Similar to GB:M29450 SP:P16497 GB:M31067 PID:143333 PID:143631 percent identity: 26.63; identified by sequence similarity; putative. (438 aa)    
Predicted Functional Partners:
thsB
Thermosome, subunit beta (thsB); Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
  
 0.720
AF_2419
Response regulator; Similar to PID:1086465 percent identity: 37.93; identified by sequence similarity; putative.
 
 
 
 0.688
metG
methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
    0.657
AF_1256
Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative.
 
 
 
 0.654
AF_1898
Response regulator; Similar to PID:940149 percent identity: 48.70; identified by sequence similarity; putative.
 
 
 
 0.649
AF_0449
Response regulator; Similar to GB:M59781 SP:P24072 PID:142682 GB:AL009126 percent identity: 38.14; identified by sequence similarity; putative.
 
 
 
 0.620
AF_1063
Response regulator; Similar to PID:940149 percent identity: 36.28; identified by sequence similarity; putative.
 
 
 
 0.620
AF_1384
Response regulator; Similar to PID:940149 percent identity: 44.74; identified by sequence similarity; putative.
 
 
 
 0.618
AF_2249
Response regulator; Similar to PID:940149 percent identity: 44.83; identified by sequence similarity; putative.
 
 
 
 0.613
pcn
Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
  
 0.582
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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