Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1473Response regulator; Similar to PID:1086465 percent identity: 38.64; identified by sequence similarity; putative. (133 aa)    
Predicted Functional Partners:
AF_1472
Signal-transducing histidine kinase; Similar to PID:1652120 percent identity: 30.40; identified by sequence similarity; putative.
 
     0.894
AF_1483
Signal-transducing histidine kinase; Similar to PID:1652120 percent identity: 27.72; identified by sequence similarity; putative.
 
     0.698
AF_1515
Signal-transducing histidine kinase; Similar to SP:P45670 PID:599601 percent identity: 24.05; identified by sequence similarity; putative.
 
 
 
 0.675
AF_0208
Signal-transducing histidine kinase; Similar to PID:1001492 PID:1001594 percent identity: 27.88; identified by sequence similarity; putative.
 
 
 
 0.664
cheB
Protein-glutamate methylesterase (cheB); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.659
AF_2109
Signal-transducing histidine kinase; Similar to GB:M29450 SP:P16497 GB:M31067 PID:143333 PID:143631 percent identity: 26.96; identified by sequence similarity; putative.
 
 
 
 0.646
AF_1044
Purine-binding chemotaxis protein (cheW); Similar to GB:M26411 SP:P21821 PID:148348 percent identity: 40.41; identified by sequence similarity; putative.
  
 
 0.641
AF_0770
Signal-transducing histidine kinase; Similar to GB:M29450 SP:P16497 GB:M31067 PID:143333 PID:143631 percent identity: 23.04; identified by sequence similarity; putative.
 
 
 
 0.640
AF_1184
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 29.81; identified by sequence similarity; putative.
 
 
 
 0.640
AF_1040
Chemotaxis histidine kinase (cheA); Similar to PID:940147 SP:Q56310 percent identity: 41.92; identified by sequence similarity; putative.
  
  
 0.601
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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