Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_1494Predicted coding region AF_1494; Hypothetical protein; identified by GeneMark; putative. (235 aa)    
Predicted Functional Partners:
AF_0861
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hps-1); Similar to GB:L77117 SP:Q58842 PID:1592092 percent identity: 30.59; identified by sequence similarity; putative.
 
 
  0.943
AF_0458
Phosphomannomutase (pmm); Similar to GB:L77117 PID:1591745 percent identity: 39.46; identified by sequence similarity; putative; Belongs to the phosphohexose mutase family.
    
 0.930
AF_1796
Conserved hypothetical protein; Similar to SP:P42404 PID:710636 PID:1438846 PID:1805417 GB:AL009126 percent identity: 36.61; identified by sequence similarity; putative; Belongs to the SIS family. PHI subfamily.
  
 
  0.930
AF_1097
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase (manC); Similar to PID:559389 percent identity: 43.08; identified by sequence similarity; putative; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
  0.925
AF_0035
Mannosephosphate isomerase, putative; Similar to GB:D16594 PID:451216 SP:Q59935 percent identity: 31.30; identified by sequence similarity; putative.
    
  0.919
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.907
AF_0242
Glucose-1-phosphate thymidylyltransferase (graD-1); Similar to PID:763512 percent identity: 27.69; identified by sequence similarity; putative.
 
      0.896
gap
Glyceraldehyde 3-phosphate dehydrogenase (gap); Similar to SP:P10618 PID:149792 percent identity: 56.59; identified by sequence similarity; putative.
    
 0.871
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.846
eno
Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.835
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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