| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_0840 | aroA-2 | AF_0840 | AF_1497 | long-chain-fatty-acid--CoA ligase (fadD-4); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.12; identified by sequence similarity; putative. | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.828 |
| AF_1510 | aroA-2 | AF_1510 | AF_1497 | long-chain-fatty-acid--CoA ligase (fadD-6); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 35.99; identified by sequence similarity; putative. | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.873 |
| AF_1772 | AF_2368 | AF_1772 | AF_2368 | long-chain-fatty-acid--CoA ligase (fadD-7); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.67; identified by sequence similarity; putative. | long-chain-fatty-acid--CoA ligase (fadD-9); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.75; identified by sequence similarity; putative. | 0.803 |
| AF_1772 | aroA-2 | AF_1772 | AF_1497 | long-chain-fatty-acid--CoA ligase (fadD-7); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.67; identified by sequence similarity; putative. | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.863 |
| AF_2368 | AF_1772 | AF_2368 | AF_1772 | long-chain-fatty-acid--CoA ligase (fadD-9); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.75; identified by sequence similarity; putative. | long-chain-fatty-acid--CoA ligase (fadD-7); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.67; identified by sequence similarity; putative. | 0.803 |
| AF_2368 | aroA-2 | AF_2368 | AF_1497 | long-chain-fatty-acid--CoA ligase (fadD-9); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.75; identified by sequence similarity; putative. | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.852 |
| aroA-2 | AF_0840 | AF_1497 | AF_0840 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | long-chain-fatty-acid--CoA ligase (fadD-4); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.12; identified by sequence similarity; putative. | 0.828 |
| aroA-2 | AF_1510 | AF_1497 | AF_1510 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | long-chain-fatty-acid--CoA ligase (fadD-6); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 35.99; identified by sequence similarity; putative. | 0.873 |
| aroA-2 | AF_1772 | AF_1497 | AF_1772 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | long-chain-fatty-acid--CoA ligase (fadD-7); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.67; identified by sequence similarity; putative. | 0.863 |
| aroA-2 | AF_2368 | AF_1497 | AF_2368 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | long-chain-fatty-acid--CoA ligase (fadD-9); Similar to SP:P29212 GB:L02649 GB:X70994 PID:581070 GB:U00096 percent identity: 38.75; identified by sequence similarity; putative. | 0.852 |
| aroA-2 | aroB | AF_1497 | AF_0229 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Conserved hypothetical protein; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.954 |
| aroA-2 | aroC | AF_1497 | AF_0670 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase (aroC); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.999 |
| aroA-2 | aroD | AF_1497 | AF_0228 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase (aroD); Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.967 |
| aroA-2 | aroE | AF_1497 | AF_2327 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase (aroE); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.999 |
| aroA-2 | aroK | AF_1497 | AF_0520 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Conserved hypothetical protein; Similar to GB:L77117 PID:1500322 percent identity: 34.44; identified by sequence similarity; putative. | 0.950 |
| aroA-2 | trpCD | AF_1497 | AF_1604 | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity). | 0.950 |
| aroB | aroA-2 | AF_0229 | AF_1497 | Conserved hypothetical protein; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 5-enolpyruvylshikimate 3-phosphate synthase (aroA); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.954 |
| aroB | aroC | AF_0229 | AF_0670 | Conserved hypothetical protein; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | Chorismate synthase (aroC); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.952 |
| aroB | aroD | AF_0229 | AF_0228 | Conserved hypothetical protein; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 3-dehydroquinate dehydratase (aroD); Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.988 |
| aroB | aroE | AF_0229 | AF_2327 | Conserved hypothetical protein; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | Shikimate 5-dehydrogenase (aroE); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.928 |
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