close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1515Signal-transducing histidine kinase; Similar to SP:P45670 PID:599601 percent identity: 24.05; identified by sequence similarity; putative. (338 aa)    
Predicted Functional Partners:
AF_2419
Response regulator; Similar to PID:1086465 percent identity: 37.93; identified by sequence similarity; putative.
 
 
 
 0.800
AF_1898
Response regulator; Similar to PID:940149 percent identity: 48.70; identified by sequence similarity; putative.
 
 
 
 0.777
AF_1256
Response regulator; Similar to PID:940149 percent identity: 42.45; identified by sequence similarity; putative.
 
 
 
 0.771
AF_0449
Response regulator; Similar to GB:M59781 SP:P24072 PID:142682 GB:AL009126 percent identity: 38.14; identified by sequence similarity; putative.
 
 
 
 0.759
AF_1384
Response regulator; Similar to PID:940149 percent identity: 44.74; identified by sequence similarity; putative.
 
 
 
 0.755
AF_1473
Response regulator; Similar to PID:1086465 percent identity: 38.64; identified by sequence similarity; putative.
 
 
 
 0.754
AF_2249
Response regulator; Similar to PID:940149 percent identity: 44.83; identified by sequence similarity; putative.
 
 
 
 0.748
AF_1063
Response regulator; Similar to PID:940149 percent identity: 36.28; identified by sequence similarity; putative.
 
 
 
 0.747
AF_1042
Chemotaxis response regulator (cheY); Similar to PID:940149 percent identity: 62.93; identified by sequence similarity; putative.
 
 
 
 0.613
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 
 0.547
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.