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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sfsASugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 30.96; identified by sequence similarity; putative; Belongs to the SfsA family. (219 aa)    
Predicted Functional Partners:
AF_1318
Predicted coding region AF_1318; Might play a role in defense against invading genetic elements, using short DNA sequences as guides to bind complementary target strands, resulting in slicing of the target nucleic acid (By similarity). Binds nucleic acids with decreasing affinity in the following order; ssDNA, ssRNA, dsDNA, RNA-DNA, RNA-RNA. Association of the 5' seed region of the guide strand (nucleotides 2-7) with AfPiwi increases affinity for the corresponding target strand; the greatest increase in affinity is for guide DNA with target RNA.
      
 0.892
AF_1517
Conserved hypothetical protein; Similar to PID:1196899 percent identity: 36.78; identified by sequence similarity; putative.
       0.773
AF_1520
Flavoprotein (fprA-2); Similar to GB:L77117 SP:Q58142 PID:1591446 percent identity: 47.15; identified by sequence similarity; putative.
 
     0.755
AF_1519
Iron-sulfur flavoprotein (isf-2); Redox-active protein probably involved in electron transport. Belongs to the SsuE family. Isf subfamily.
       0.702
AF_1518
DNA/pantothenate metabolism flavoprotein, putative; Similar to GB:L77117 SP:Q58140 PID:1499547 percent identity: 51.40; identified by sequence similarity; putative.
       0.701
AF_1521
Conserved hypothetical protein; Removes ADP-ribose from asparatate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Catalyzes removal of a phosphate group from ADP-ribose 1''-phosphate (Appr1p), but with low efficiency.
       0.550
AF_2157
Conserved hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
     
 0.432
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.