Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1520Flavoprotein (fprA-2); Similar to GB:L77117 SP:Q58142 PID:1591446 percent identity: 47.15; identified by sequence similarity; putative. (488 aa)    
Predicted Functional Partners:
feR
Conserved hypothetical protein; Catalyzes the reduction of bound ferric iron (Fe(3+)) in a variety of iron chelators (siderophores) using NAD(P)H as the electron donor, resulting in the release of Fe(2+). Not active with uncomplexed Fe(3+). Also reduces FMN and FAD, but not riboflavin. Belongs to the non-flavoprotein flavin reductase family.
   
 0.925
AF_0951
NADH oxidase (noxA-4); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 36.71; identified by sequence similarity; putative.
    
 0.902
AF_1519
Iron-sulfur flavoprotein (isf-2); Redox-active protein probably involved in electron transport. Belongs to the SsuE family. Isf subfamily.
 
  
 0.852
AF_1858
NADH oxidase (noxA-5); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 34.00; identified by sequence similarity; putative.
    
 0.843
AF_0395
NADH oxidase (noxA-2); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 35.45; identified by sequence similarity; putative.
    
 0.816
AF_1518
DNA/pantothenate metabolism flavoprotein, putative; Similar to GB:L77117 SP:Q58140 PID:1499547 percent identity: 51.40; identified by sequence similarity; putative.
       0.781
sfsA
Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 30.96; identified by sequence similarity; putative; Belongs to the SfsA family.
 
     0.744
AF_0400
NADH oxidase (noxA-3); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 40.85; identified by sequence similarity; putative.
    
 0.727
AF_1517
Conserved hypothetical protein; Similar to PID:1196899 percent identity: 36.78; identified by sequence similarity; putative.
       0.703
AF_0344
Desulfoferrodoxin, putative; Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
  
  
 0.637
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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