Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1528Conserved hypothetical protein; Similar to GB:L77117 PID:1499710 percent identity: 23.20; identified by sequence similarity; putative. (136 aa)    
Predicted Functional Partners:
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
       0.845
AF_1245
Na+/H+ antiporter (napA-2); Similar to SP:P26235 PID:148316 percent identity: 28.41; identified by sequence similarity; putative.
   
    0.782
AF_0524
Predicted coding region AF_0524; Hypothetical protein; identified by GeneMark; putative.
   
    0.604
AF_2302
Predicted coding region AF_2302; Hypothetical protein; identified by GeneMark; putative.
   
    0.525
AF_2046
Cytochrome oxidase, subunit I, putative; Similar to GP:1773053 percent identity: 25.14; identified by sequence similarity; putative.
   
    0.501
rpl21e
LSU ribosomal protein L21E (rpl21E); Similar to GB:L77117 SP:P54013 PID:1590841 percent identity: 53.19; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
       0.495
AF_1530
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60351 PID:1590840 percent identity: 45.28; identified by sequence similarity; putative.
       0.495
AF_1524
Predicted coding region AF_1524; Hypothetical protein; identified by GeneMark; putative.
       0.492
AF_1525
Conserved hypothetical protein; Similar to SP:P54437 PID:1303709 GB:AL009126 percent identity: 28.51; identified by sequence similarity; putative.
       0.492
AF_1526
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57997 PID:1591284 percent identity: 27.37; identified by sequence similarity; putative.
       0.492
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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