STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1531Conserved hypothetical protein; Similar to GB:L77117 SP:Q60345 PID:1498798 percent identity: 43.68; identified by sequence similarity; putative. (195 aa)    
Predicted Functional Partners:
rpl21e
LSU ribosomal protein L21E (rpl21E); Similar to GB:L77117 SP:P54013 PID:1590841 percent identity: 53.19; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
 
  
 0.933
AF_1530
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60351 PID:1590840 percent identity: 45.28; identified by sequence similarity; putative.
 
   
 0.816
rsmA
Dimethyladenosine transferase (ksgA); Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
     
 0.789
AF_1532
Conserved hypothetical protein; Similar to GB:L77117 PID:1591589 percent identity: 41.27; identified by sequence similarity; putative.
 
     0.714
dnaG
Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.697
eif5a
Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
     0.684
cca
tRNA nucleotidyltransferase (cca); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
   
 0.676
rpl18e
LSU ribosomal protein L18E (rpl18E); Similar to SP:P12733 GB:M76567 PID:148774 PID:148776 percent identity: 53.85; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL18 family.
 
     0.674
spt5
LSU ribosomal protein L24A (rpl24A); Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.672
rrp4
Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (Probable); Belongs to the RRP4 family.
 
     0.669
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.