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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1538Conserved hypothetical protein; Similar to GB:L42023 SP:P44051 PID:1005750 PID:1220865 PID:1205020 percent identity: 37.20; identified by sequence similarity; putative. (486 aa)    
Predicted Functional Partners:
AF_1537
Carboxylesterase (est-2); Similar to GB:D14529 PID:402521 percent identity: 29.02; identified by sequence similarity; putative.
       0.678
AF_1199
Glutaconate CoA-transferase, subunit A (gctA); Similar to PID:559392 percent identity: 31.86; identified by sequence similarity; putative; Belongs to the 3-oxoacid CoA-transferase subunit A family.
 
  
 0.658
sucD1
succinyl-CoA synthetase, alpha subunit (sucD-1); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.472
sucC1
succinyl-CoA synthetase, beta subunit (sucC-1); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.472
AF_0973
Bile acid-inducible operon protein F (baiF-1); Similar to GP:1799782 percent identity: 30.77; identified by sequence similarity; putative.
     
 0.458
AF_0974
Bile acid-inducible operon protein F (baiF-2); Similar to GP:1799782 percent identity: 30.03; identified by sequence similarity; putative.
     
 0.458
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
   
  
 0.452
AF_1536
Glutaredoxin (grx-1); Similar to PID:1652611 percent identity: 34.29; identified by sequence similarity; putative.
       0.447
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.426
AF_0024
Alcohol dehydrogenase, iron-containing; Similar to GB:M26941 SP:P13604 PID:144714 percent identity: 36.18; identified by sequence similarity; putative.
     
 0.422
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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