Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kptA2Conserved hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity). (216 aa)    
Predicted Functional Partners:
AF_1554
Thioredoxin reductase (trxB); Similar to PID:1171125 SP:P52213 percent identity: 45.21; identified by sequence similarity; putative.
       0.705
thiL
Thiamine monophosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.618
AF_1552
Conserved hypothetical protein; Similar to GB:L10328 SP:P31437 PID:290509 GB:U00096 PID:1790092 percent identity: 25.65; identified by sequence similarity; putative.
  
    0.571
AF_1555
Predicted coding region AF_1555; Hypothetical protein; identified by GeneMark; putative.
       0.486
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
      
 0.455
AF_1551
Octaprenyl-diphosphate synthase (ispB); Similar to GB:L42023 SP:P44916 PID:1005963 PID:1220984 PID:1205128 percent identity: 33.20; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family.
       0.438
AF_1521
Conserved hypothetical protein; Removes ADP-ribose from asparatate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Catalyzes removal of a phosphate group from ADP-ribose 1''-phosphate (Appr1p), but with low efficiency.
 
   
 0.433
AF_1724
Dinitrogenase reductase activating glycohydrolase (draG); Similar to GB:L77117 PID:1591815 percent identity: 37.92; identified by sequence similarity; putative; Belongs to the ADP-ribosylglycohydrolase family.
 
   
 0.432
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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