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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1556Conserved hypothetical protein; Similar to PID:1652988 percent identity: 38.22; identified by sequence similarity; putative. (274 aa)    
Predicted Functional Partners:
AF_1275
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57629 PID:1498937 percent identity: 51.82; identified by sequence similarity; putative.
  
 0.948
AF_2097
Conserved hypothetical protein; Similar to GB:L77117 PID:1592033 percent identity: 34.93; identified by sequence similarity; putative; Belongs to the LarC family.
  
 0.948
AF_0049
Predicted coding region AF_0049; Hypothetical protein; identified by GeneMark; putative.
 
  
 0.859
AF_1843
Cobalamin biosynthesis protein (cbiM-2); May be involved in nickel transport; Belongs to the CbiM family. NikM subfamily.
 
    0.676
cbiM
Cobalamin biosynthesis protein (cbiM-1); Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.626
smc
Chromosome segregation protein (smc1); Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
     0.483
AF_1555
Predicted coding region AF_1555; Hypothetical protein; identified by GeneMark; putative.
       0.480
nth
Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.448
AF_1245
Na+/H+ antiporter (napA-2); Similar to SP:P26235 PID:148316 percent identity: 28.41; identified by sequence similarity; putative.
  
    0.409
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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