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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1580Conserved hypothetical protein; Similar to PID:1653807 percent identity: 34.00; identified by sequence similarity; putative. (166 aa)    
Predicted Functional Partners:
AF_1559
Conserved hypothetical protein; Similar to GB:L77117 PID:1591768 percent identity: 27.88; identified by sequence similarity; putative.
 
 
 0.999
smc
Chromosome segregation protein (smc1); Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.923
rad50
Purine NTPase, putative; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
 
  
 0.617
nusA
Transcription termination-antitermination factor NusA, putative; Participates in transcription termination. Belongs to the NusA family.
 
    0.571
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.562
AF_1581
Predicted coding region AF_1581; Hypothetical protein; identified by GeneMark; putative.
       0.545
AF_1557
Predicted coding region AF_1557; Hypothetical protein; identified by GeneMark; putative.
       0.534
AF_0781
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
    0.493
AF_2118
Inosine monophosphate dehydrogenase (guaB-2); Similar to GB:L77117 SP:Q58069 PID:1592300 percent identity: 31.86; identified by sequence similarity; putative.
 
     0.490
infB
Translation initiation factor IF-2 (infB); Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
     
 0.482
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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