STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1581Predicted coding region AF_1581; Hypothetical protein; identified by GeneMark; putative. (106 aa)    
Predicted Functional Partners:
AF_1039
Conserved hypothetical protein; Similar to GB:M20144 SP:P40403 PID:289302 GB:AL009126 percent identity: 26.56; identified by sequence similarity; putative.
    
   0.735
cobB2
Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
  
    0.549
cobB1
Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
  
    0.549
AF_1580
Conserved hypothetical protein; Similar to PID:1653807 percent identity: 34.00; identified by sequence similarity; putative.
       0.545
AF_0673
Mercuric resistance operon regulatory protein (merR); Similar to SP:P22853 PID:1129093 percent identity: 33.04; identified by sequence similarity; putative.
  
  
 0.539
AF_0348
Conserved hypothetical protein; Similar to PID:1196911 percent identity: 32.76; identified by sequence similarity; putative.
     
 0.528
AF_0143
Conserved hypothetical protein; Similar to GB:L77117 PID:1592228 percent identity: 25.53; identified by sequence similarity; putative.
  
  
 0.494
AF_1606
Spermidine/putrescine ABC transporter, permease protein (potC); Similar to GB:M64519 SP:P23859 PID:147328 GB:U00096 PID:1651551 percent identity: 39.48; identified by sequence similarity; putative.
   
 
 0.481
AF_0700
Aspartate kinase (lysC); Similar to GB:L77117 SP:Q57991 PID:1591278 percent identity: 49.13; identified by sequence similarity; putative; Belongs to the aspartokinase family.
     
 0.478
AF_0155
Predicted coding region AF_0155; Hypothetical protein; identified by GeneMark; putative.
  
    0.477
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.