close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1587Ribulose bisphosphate carboxylase, large subunit (rbcL-1); May be involved in sulfur metabolism and oxidative stress response. Does not show RuBisCO activity (By similarity). (437 aa)    
Predicted Functional Partners:
AF_1588
Conserved hypothetical protein; Similar to PID:1001103 PID:1001125 percent identity: 25.75; identified by sequence similarity; putative.
       0.773
AF_2037
Translation initiation factor eIF-2B, subunit delta (eif2BD); Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
 
  
 0.698
AF_0480
Fuculose-1-phosphate aldolase (fucA); Similar to GB:L77117 SP:Q58813 PID:1592067 percent identity: 31.84; identified by sequence similarity; putative.
  
  
 0.667
AF_1589
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58096 PID:1591398 percent identity: 37.62; identified by sequence similarity; putative.
       0.628
nreB
Predicted coding region AF_1590; Involved in DNA damage repair.
       0.615
AF_0370
Translation initiation factor eIF-2B, subunit delta (eif2BD); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
  
 0.562
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
      
 0.525
katG
Peroxidase / catalase (perA); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity.
   
    0.457
AF_0024
Alcohol dehydrogenase, iron-containing; Similar to GB:M26941 SP:P13604 PID:144714 percent identity: 36.18; identified by sequence similarity; putative.
     
 0.439
AF_0339
Alcohol dehydrogenase, iron-containing; Similar to GB:M26941 SP:P13604 PID:144714 percent identity: 37.40; identified by sequence similarity; putative.
     
 0.439
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.