Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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speHConserved hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (112 aa)    
Predicted Functional Partners:
speE
Spermidine synthase (speE); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
 
 0.998
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.926
bpsA
Conserved hypothetical protein; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
 
     0.926
mat
Conserved hypothetical protein; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
     
 0.904
AF_1612
Cationic amino acid transporter (cat-1); Similar to GB:L77117 SP:Q58026 PID:1591319 percent identity: 29.51; identified by sequence similarity; putative.
  
  
 0.633
AF_0218
TRK potassium uptake system protein (trkA-1); Similar to GB:X74307 SP:P39449 PID:414170 percent identity: 30.17; identified by sequence similarity; putative.
     
 0.627
gap
Glyceraldehyde 3-phosphate dehydrogenase (gap); Similar to SP:P10618 PID:149792 percent identity: 56.59; identified by sequence similarity; putative.
  
  
 0.606
AF_1606
Spermidine/putrescine ABC transporter, permease protein (potC); Similar to GB:M64519 SP:P23859 PID:147328 GB:U00096 PID:1651551 percent identity: 39.48; identified by sequence similarity; putative.
  
  
 0.556
AF_0646
Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family.
     
 0.474
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.461
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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