STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1623Aspartate aminotransferase (aspB-3); Similar to GB:L77117 SP:Q60317 PID:1592252 percent identity: 39.41; identified by sequence similarity; putative. (390 aa)    
Predicted Functional Partners:
AF_1622
Leucine responsive regulatory protein (lrp); Similar to GP:1262197 percent identity: 29.05; identified by sequence similarity; putative.
 
   
 0.928
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
  
 0.919
AF_1624
Molybdopterin converting factor, subunit 1 (moaD); Similar to SP:P30748 PID:42011 GB:U00096 PID:1651357 PID:1787002 percent identity: 36.59; identified by sequence similarity; putative.
     
 0.775
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
  
 
 0.638
AF_1417
Aspartate aminotransferase (aspC); Similar to GB:L77117 PID:1591623 percent identity: 49.29; identified by sequence similarity; putative.
  
 
 0.618
AF_1625
Predicted coding region AF_1625; Hypothetical protein; identified by GeneMark; putative.
       0.566
AF_1621
Conserved hypothetical protein; Similar to SP:P33019 PID:405879 GB:U00096 PID:1788482 percent identity: 29.15; identified by sequence similarity; putative.
       0.565
AF_1620
Signal-transducing histidine kinase, putative; Similar to PID:1652841 percent identity: 26.18; identified by sequence similarity; putative.
       0.552
icd
Isocitrate dehydrogenase, NADP (icd); Similar to GB:J02799 SP:P08200 PID:146432 GB:U00096 PID:1651560 percent identity: 57.18; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
  
 0.544
AF_0197
acetyl-CoA synthetase (acs-1); Similar to SP:P27550 PID:396404 PID:148105 GB:U00096 PID:1790505 percent identity: 27.14; identified by sequence similarity; putative.
  
 
 0.542
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.