Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1645Pantothenate metabolism flavoprotein (dfp); Similar to GB:L77117 PID:1591587 percent identity: 42.42; identified by sequence similarity; putative. (404 aa)    
Predicted Functional Partners:
AF_0927
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57662 PID:1498984 percent identity: 47.83; identified by sequence similarity; putative.
 
  
 0.981
AF_1646
Conserved hypothetical protein; Similar to GB:L77117 PID:1591632 percent identity: 34.23; identified by sequence similarity; putative.
 
   
 0.945
coaD
Conserved hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family.
    
 0.912
AF_1422
Aspartate racemase; Similar to GP:1545809 percent identity: 28.02; identified by sequence similarity; putative.
    
  0.905
AF_1238
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
       0.879
AF_2129
Aspartate aminotransferase (aspB-2); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 45.38; identified by sequence similarity; putative.
 
 0.871
AF_2366
Aspartate aminotransferase (aspB-1); Similar to GB:L77117 SP:Q60317 PID:1592252 percent identity: 42.31; identified by sequence similarity; putative.
  
 0.854
AF_1647
Conserved hypothetical protein; Similar to GB:X52543 PID:46506 SP:P55177 percent identity: 26.56; identified by sequence similarity; putative.
 
   
 0.827
AF_1644
Tungsten formylmethanofuran dehydrogenase, subunit F (fwdF); Similar to GB:L77117 PID:1591792 percent identity: 38.21; identified by sequence similarity; putative.
       0.809
pth
Conserved hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
   
 
 0.765
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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