Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_1646Conserved hypothetical protein; Similar to GB:L77117 PID:1591632 percent identity: 34.23; identified by sequence similarity; putative. (261 aa)    
Predicted Functional Partners:
AF_0927
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57662 PID:1498984 percent identity: 47.83; identified by sequence similarity; putative.
 
  
 0.992
AF_1695
Thiamine biosynthesis protein (apbA); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
    
 0.953
AF_1645
Pantothenate metabolism flavoprotein (dfp); Similar to GB:L77117 PID:1591587 percent identity: 42.42; identified by sequence similarity; putative.
 
   
 0.945
AF_1238
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
       0.879
htpX
Heat shock protein (htpX); Similar to GB:L77117 PID:1592249 percent identity: 32.95; identified by sequence similarity; putative; Belongs to the peptidase M48B family.
  
    0.863
AF_1644
Tungsten formylmethanofuran dehydrogenase, subunit F (fwdF); Similar to GB:L77117 PID:1591792 percent identity: 38.21; identified by sequence similarity; putative.
 
     0.840
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Incorrectly charged aminoacyl-tRNA(Ala) is also edited in situ by the editing domain.
  
    0.811
AF_1647
Conserved hypothetical protein; Similar to GB:X52543 PID:46506 SP:P55177 percent identity: 26.56; identified by sequence similarity; putative.
       0.773
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
  
    0.731
AF_1648
Bacteriochlorophyll synthase, 33 kDa subunit; Similar to PID:1001103 PID:1001139 percent identity: 27.92; identified by sequence similarity; putative.
       0.727
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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