ala protein (Archaeoglobus fulgidus) - STRING interaction network

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ala

Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...] (322 aa)

Predicted Functional Partners:

AF_1794

0.892

AF_1666

0.791

AF_0274

0.638

lysA

0.636

AF_1664

0.558

AF_0646

0.556

AF_2034

0.525

AF_2408

0.521

dapA

0.514

sat

0.473

Your Current Organism:

Archaeoglobus fulgidus

NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AF_0274	AF_0646	AF_0274	AF_0646	Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.	Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family.	0.461
AF_0274	ala	AF_0274	AF_1665	Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	0.638
AF_0274	dapA	AF_0274	AF_0910	Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.	Dihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.506
AF_0646	AF_0274	AF_0646	AF_0274	Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family.	Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.	0.461
AF_0646	ala	AF_0646	AF_1665	Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family.	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	0.556
AF_0646	lysA	AF_0646	AF_0800	Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family.	Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.694
AF_1664	AF_1666	AF_1664	AF_1666	Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.	Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative.	0.525
AF_1664	ala	AF_1664	AF_1665	Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	0.558
AF_1664	lysA	AF_1664	AF_0800	Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.	Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.436
AF_1666	AF_1664	AF_1666	AF_1664	Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative.	Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.	0.525
AF_1666	ala	AF_1666	AF_1665	Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative.	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	0.791
AF_1666	sat	AF_1666	AF_1667	Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative.	Sulfate adenylyltransferase (sat); Similar to PID:1653421 percent identity: 28.39; identified by sequence similarity; putative; Belongs to the sulfate adenylyltransferase family.	0.469
AF_1794	ala	AF_1794	AF_1665	Myo-inositol-1-phosphate synthase (ino1); Similar to SP:P11986 PID:1015571 PID:854544 percent identity: 32.24; identified by sequence similarity; putative.	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	0.892
AF_2034	ala	AF_2034	AF_1665	X-pro aminopeptidase (pepQ); Similar to GB:L77117 SP:Q58216 PID:1591498 percent identity: 34.63; identified by sequence similarity; putative; Belongs to the peptidase M24B family.	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	0.525
AF_2034	dapA	AF_2034	AF_0910	X-pro aminopeptidase (pepQ); Similar to GB:L77117 SP:Q58216 PID:1591498 percent identity: 34.63; identified by sequence similarity; putative; Belongs to the peptidase M24B family.	Dihydrodipicolinate synthase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.420
AF_2408	ala	AF_2408	AF_1665	Conserved hypothetical protein; Similar to GP:1881347 percent identity: 28.89; identified by sequence similarity; putative.	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	0.521
ala	AF_0274	AF_1665	AF_0274	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.	0.638
ala	AF_0646	AF_1665	AF_0646	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family.	0.556
ala	AF_1664	AF_1665	AF_1664	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.	0.558
ala	AF_1666	AF_1665	AF_1666	Ornithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...]	Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative.	0.791

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