STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alaOrnithine cyclodeaminase (arcB); Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate. Its physiological role is not known. Can not use NADP(+) instead of NAD(+) as a cosubstrate. In the deamination direction, can also efficiently use L-2-aminobutyrate as substrate. In the reductive amination direction, also exhibits high activity with 2-oxobutyrate and oxaloacetate as substrate. In contrast to bacterial homologs, does not exhibit any ornithine cyclodeaminase activity; Belongs to the ornithine cycl [...] (322 aa)    
Predicted Functional Partners:
AF_1794
Myo-inositol-1-phosphate synthase (ino1); Similar to SP:P11986 PID:1015571 PID:854544 percent identity: 32.24; identified by sequence similarity; putative.
      
 0.850
dld
D-lactate dehydrogenase, cytochrome-type (dld); Converts D-lactate to pyruvate. Cannot use NAD(+), cytochrome C, methylene blue or dimethylnaphthoquinone as acceptors. Active in vitro with artificial electron acceptors such as 2,6- dichlorophenolindophenol, but the physiological acceptor is not yet known.
    
 0.821
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
  0.813
korA
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA); Similar to GB:L77117 PID:1592279 percent identity: 52.34; identified by sequence similarity; putative.
    
 0.806
AF_0749
2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA); Similar to GP:1565183 percent identity: 33.70; identified by sequence similarity; putative.
    
 0.806
AF_1701
Pyruvate ferredoxin oxidoreductase, subunit alpha (porA); Similar to PID:1590995 percent identity: 50.27; identified by sequence similarity; putative.
    
 0.806
AF_2053
2-ketoisovalerate ferredoxin oxidoreductase, subunit alpha (vorA); Similar to PID:1197363 percent identity: 41.16; identified by sequence similarity; putative.
    
 0.806
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
    
  0.802
AF_1422
Aspartate racemase; Similar to GP:1545809 percent identity: 28.02; identified by sequence similarity; putative.
    
  0.801
AF_1700
Pyruvate ferredoxin oxidoreductase, subunit delta (porD); Similar to PID:1197359 percent identity: 53.12; identified by sequence similarity; putative.
    
  0.801
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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