Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_1670Adenylylsulfate reductase, subunit A (aprA); Similar to GB:X63435 PID:38809 percent identity: 95.98; identified by sequence similarity; putative. (643 aa)    
Predicted Functional Partners:
AF_1669
Adenylylsulfate reductase, subunit B (aprB); Similar to GB:X63435 PID:443816 GB:AE000782 percent identity: 100.00; identified by sequence similarity; putative.
 
 0.999
sat
Sulfate adenylyltransferase (sat); Similar to PID:1653421 percent identity: 28.39; identified by sequence similarity; putative; Belongs to the sulfate adenylyltransferase family.
 
 
 0.994
AF_0682
Succinate dehydrogenase, iron-sulfur subunit B (sdhB); Similar to GB:X70908 PID:396212 percent identity: 51.27; identified by sequence similarity; putative.
 
 0.980
AF_0683
Succinate dehydrogenase, subunit C (sdhC); Similar to GP:1524299 percent identity: 36.56; identified by sequence similarity; putative.
  
 0.975
dsrA
Sulfite reductase, subunit alpha (dsrA); Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration.
 
 
 0.965
dsrB
Sulfite reductase, subunit beta (dsrB); Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration.
 
 
 0.963
hmeC
Nitrate reductase, gamma subunit, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
 
  
 0.948
hmeA
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
  
 
 0.945
hmeD
Heterodisulfide reductase, subunit D, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
 
  
 0.945
sdhD
Succinate dehydrogenase, subunit D (sdhD); Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
 
 0.935
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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