Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1675Predicted coding region AF_1675; Hypothetical protein; identified by GeneMark; putative. (127 aa)    
Predicted Functional Partners:
AF_1554
Thioredoxin reductase (trxB); Similar to PID:1171125 SP:P52213 percent identity: 45.21; identified by sequence similarity; putative.
  
 
 0.954
AF_0270
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.851
AF_2220
Predicted coding region AF_2220; Hypothetical protein; identified by GeneMark; putative.
  
 0.837
cobB1
Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
     
 0.589
egsA
Sn-glycerol-1-phosphate dehydrogenase (gldA); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
       0.588
AF_2192
Cytochrome C-type biogenesis protein (nrfE); Similar to GP:1790511 percent identity: 36.13; identified by sequence similarity; putative.
  
  
 0.564
ndk
Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
 0.544
AF_1980
Heme exporter protein C (helC); Similar to SP:P29961 GB:X63462 PID:46026 percent identity: 29.02; identified by sequence similarity; putative.
  
  
 0.532
AF_0142
Cytochrome C oxidase, subunit II, putative; Similar to GB:L09121 PID:155085 SP:P98052 percent identity: 38.04; identified by sequence similarity; putative.
   
 
 0.521
AF_1057
Cytochrome C-type biogenesis protein (ccdA); Similar to SP:P45706 PID:870925 PID:1405449 GB:AL009126 percent identity: 30.69; identified by sequence similarity; putative.
  
  
 0.521
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.