node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_0130 | cobB1 | AF_0130 | AF_1676 | Acetylpolyamine aminohydrolase (aphA); Probable deacetylase; Belongs to the histone deacetylase family. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_0130 | cobB2 | AF_0130 | AF_0112 | Acetylpolyamine aminohydrolase (aphA); Probable deacetylase; Belongs to the histone deacetylase family. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_0690 | cobB1 | AF_0690 | AF_1676 | Predicted coding region AF_0690; Hypothetical protein; identified by GeneMark; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_0690 | cobB2 | AF_0690 | AF_0112 | Predicted coding region AF_0690; Hypothetical protein; identified by GeneMark; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_0922 | cobB1 | AF_0922 | AF_1676 | Predicted coding region AF_0922; Hypothetical protein; identified by GeneMark; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.767 |
AF_0922 | cobB2 | AF_0922 | AF_0112 | Predicted coding region AF_0922; Hypothetical protein; identified by GeneMark; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.767 |
AF_1286 | cobB1 | AF_1286 | AF_1676 | Acetoin utilization protein, putative; Similar to PID:1177686 percent identity: 35.06; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_1286 | cobB2 | AF_1286 | AF_0112 | Acetoin utilization protein, putative; Similar to PID:1177686 percent identity: 35.06; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_1488 | AF_2315 | AF_1488 | AF_2315 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | 0.905 |
AF_1488 | cobB1 | AF_1488 | AF_1676 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.955 |
AF_1488 | cobB2 | AF_1488 | AF_0112 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.955 |
AF_1488 | nadE | AF_1488 | AF_1000 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.945 |
AF_1488 | nadK | AF_1488 | AF_2373 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.916 |
AF_2290 | cobB1 | AF_2290 | AF_1676 | Acetylpolyamine aminohydrolase, putative; Similar to GB:D10463 PID:520593 percent identity: 33.33; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_2290 | cobB2 | AF_2290 | AF_0112 | Acetylpolyamine aminohydrolase, putative; Similar to GB:D10463 PID:520593 percent identity: 33.33; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.694 |
AF_2315 | AF_1488 | AF_2315 | AF_1488 | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57961 PID:1591245 percent identity: 44.64; identified by sequence similarity; putative; Belongs to the archaeal NMN adenylyltransferase family. | 0.905 |
AF_2315 | cobB1 | AF_2315 | AF_1676 | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.955 |
AF_2315 | cobB2 | AF_2315 | AF_0112 | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. | 0.955 |
AF_2315 | nadE | AF_2315 | AF_1000 | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | NH(3)-dependent NAD+ synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.943 |
AF_2315 | nadK | AF_2315 | AF_2373 | Conserved hypothetical protein; Similar to GP:1591245 percent identity: 57.40; identified by sequence similarity; putative. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.916 |