Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_1695Thiamine biosynthesis protein (apbA); Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid. (294 aa)    
Predicted Functional Partners:
AF_1646
Conserved hypothetical protein; Similar to GB:L77117 PID:1591632 percent identity: 34.23; identified by sequence similarity; putative.
    
 0.953
AF_1234
Mutator protein MutT (mutT); Similar to GB:L77117 PID:1500003 percent identity: 63.64; identified by sequence similarity; putative.
      0.895
AF_1696
Small multidrug export protein (qacE); Similar to GB:X68232 GB:U13880 PID:288631 PID:43778 PID:608042 percent identity: 38.98; identified by sequence similarity; putative.
       0.729
trpS
tryptophanyl-tRNA synthetase (trpS); Similar to GB:L77117 SP:Q58810 PID:1592065 percent identity: 52.41; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.703
AF_1801
Conserved hypothetical protein; Similar to GB:L77117 PID:1592115 percent identity: 35.16; identified by sequence similarity; putative.
       0.624
ogt
methylated-DNA-protein-cysteine methyltransferase (ogt); Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.624
AF_2369
Predicted coding region AF_2369; Hypothetical protein; identified by GeneMark; putative.
       0.624
AF_1698
Conserved hypothetical protein; Similar to GB:J04423 SP:P12994 PID:455168 GB:U00096 PID:1786990 percent identity: 37.61; identified by sequence similarity; putative; Belongs to the UPF0098 family.
 
     0.623
AF_2149
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58046 PID:1591340 percent identity: 30.14; identified by sequence similarity; putative; Belongs to the UPF0111 family.
       0.616
AF_0927
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57662 PID:1498984 percent identity: 47.83; identified by sequence similarity; putative.
 
   
 0.609
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.