Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_17062-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase (pcbD); Similar to GP:1395174 percent identity: 29.41; identified by sequence similarity; putative. (238 aa)    
Predicted Functional Partners:
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
  
 
 0.640
AF_1388
DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 46.83; identified by sequence similarity; putative.
   
 0.617
AF_1822
Serine/threonine phosphatase (ppa); Similar to PID:1016001 percent identity: 31.94; identified by sequence similarity; putative.
   
 0.617
AF_1953
Predicted coding region AF_1953; Hypothetical protein; identified by GeneMark; putative.
   
 0.617
AF_1960
DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 32.71; identified by sequence similarity; putative.
   
 0.617
AF_1207
2-deoxy-D-gluconate 3-dehydrogenase (kduD); Similar to SP:Q05528 GB:X62073 PID:48986 percent identity: 45.31; identified by sequence similarity; putative.
 
 0.606
AF_1707
Predicted coding region AF_1707; Hypothetical protein; identified by GeneMark; putative.
       0.539
AF_0807
L-lactate dehydrogenase, cytochrome-type (lldD); Similar to SP:P33232 GB:L13970 PID:404695 PID:466743 GB:U00096 percent identity: 39.41; identified by sequence similarity; putative.
 
 
 0.533
AF_1708
Type I restriction-modification enzyme, R subunit; Similar to GB:L77117 SP:Q57588 PID:1592264 percent identity: 38.95; identified by sequence similarity; putative.
       0.530
AF_0675
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase (todF); Similar to GB:M64080 SP:P23133 GB:U18304 PID:151222 percent identity: 26.35; identified by sequence similarity; putative.
  
 
 0.499
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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