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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_1727Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative. (456 aa)    
Predicted Functional Partners:
AF_1098
Fumarase (fum-1); Similar to GB:L77117 SP:Q58034 PID:1591328 percent identity: 49.13; identified by sequence similarity; putative.
 
 
 0.988
mdh
L-malate dehydrogenase, NAD+-dependent (mdhA); Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate.
  
 0.970
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.952
AF_1449
Pyruvate formate-lyase 2 (pflD); Similar to SP:P32674 GB:U00006 PID:396298 GB:U00096 PID:1790388 percent identity: 37.81; identified by sequence similarity; putative.
  
 
 0.952
AF_1099
Fumarase (fum-2); Similar to GB:L77117 SP:Q58690 PID:1591932 percent identity: 53.38; identified by sequence similarity; putative.
  
 
 0.940
korB
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB); Similar to GB:L77117 PID:1591241 percent identity: 51.38; identified by sequence similarity; putative.
    
 0.936
AF_1699
Pyruvate ferredoxin oxidoreductase, subunit gamma (porG); Similar to PID:1197358 percent identity: 50.84; identified by sequence similarity; putative.
    
 0.936
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
 0.929
ppsA
Phosphoenolpyruvate synthase (ppsA); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.924
AF_2084
Oxaloacetate decarboxylase, sodium ion pump subunit (oadB); Similar to GB:M96434 SP:Q03031 PID:154198 percent identity: 59.83; identified by sequence similarity; putative.
    
 0.922
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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