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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apgM1Phosphonopyruvate decarboxylase (bcpC-2); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily. (408 aa)    
Predicted Functional Partners:
eno
Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.959
pgk
3-phosphoglycerate kinase (pgk); Similar to GB:L77117 SP:Q58058 PID:1592299 percent identity: 48.77; identified by sequence similarity; putative.
    
 0.923
serA
Phosphoglycerate dehydrogenase (serA); Similar to GB:L77117 PID:1591676 percent identity: 48.77; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.911
apgM2
Phosphonopyruvate decarboxylase (bcpC-1); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
 
0.910
AF_1752
Carbohydrate kinase, FGGY family; Similar to GB:M57384 SP:P21939 PID:149607 percent identity: 29.29; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
     
 0.863
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.836
AF_0108
Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
     
 0.830
aroA
Conserved hypothetical protein; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
     
 0.830
AF_1494
Predicted coding region AF_1494; Hypothetical protein; identified by GeneMark; putative.
     
 0.830
AF_1753
Lysophospholipase; Similar to GP:1763011 percent identity: 33.46; identified by sequence similarity; putative.
       0.773
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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