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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacZConserved hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation. (334 aa)    
Predicted Functional Partners:
AF_0458
Phosphomannomutase (pmm); Similar to GB:L77117 PID:1591745 percent identity: 39.46; identified by sequence similarity; putative; Belongs to the phosphohexose mutase family.
   
 
 0.870
AF_2029
Conserved hypothetical protein; Similar to GB:L77117 PID:1592223 percent identity: 39.41; identified by sequence similarity; putative.
   
 0.719
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
       0.635
leuD2
3-isopropylmalate dehydratase, small subunit (leuD-2); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
       0.579
AF_1760
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57997 PID:1591284 percent identity: 34.04; identified by sequence similarity; putative.
       0.575
AF_0820
Predicted coding region AF_0820; Hypothetical protein; identified by GeneMark; putative.
 
     0.569
AF_0660
Conserved hypothetical protein; Similar to SP:P42979 PID:755602 PID:1146233 GB:AL009126 percent identity: 45.10; identified by sequence similarity; putative.
 
     0.549
AF_1546
Conserved hypothetical protein; Similar to SP:P11666 PID:41424 PID:882453 GB:U00096 PID:1789291 percent identity: 33.47; identified by sequence similarity; putative.
 
   
 0.542
AF_0204
Conserved hypothetical protein; Similar to GB:L77117 PID:1591773 percent identity: 45.53; identified by sequence similarity; putative.
  
     0.499
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.473
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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